OVERVIEW CDMO SERVICES FOR VIRAL VECTORS & VACCINES

Integrated CDMO Services for Viral Vectors and Vaccines

Whether your vector is ready for manufacturing or still needs to be developed, we can help you bring your viral vector or vaccines to clinic on time, without sacrificing quality or your customization needs.

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IN A NUTSHELL

The Experienced CDMO for Cell & Gene Therapies and Viral Vaccines

If you aim to produce a viral vector or viral vaccine, let us be your trusted and highly experienced partner for development and manufacturing. From unique cell lines to scalable production, our process is tailored to your individual requirements. Expect best-in-class efficiency and competitive timelines combined with excellent customer service.

Virals_Viral Vectors & Vaccines Overview

mABs

BsMABs

Complex Recombinant
Proteins

Fusion Proteins

Cytokines

Clotting Factors

VIRUSES WE HAVE EXPERIENCE WITH

Your Virus - Our Expertise

OUR OFFERING

Integrated or Stand-Alone CDMO Services?

Producer Cell Line Development

In the rapidly advancing field of gene therapy and vaccine development, the production of viral vectors such as lentiviruses, adeno-associated viruses (AAV), adenoviruses, modified vaccinia Ankara (MVA), and other viruses is critical. Developing robust and efficient cell lines in-house for the production of these viral vectors offers significant advantages, especially when these cell lines are cultivated in suspension using chemically defined media.

Process Development

We specialize in process development for viral vectors, focusing on lentiviral vectors, AAV, adenoviruses, and poxviruses like MVA. Our expertise ensures efficient, scalable production for cell and gene therapy and vaccine development. We guide clients through every stage, from vector design and optimization to upstream/downstream development, purification, and analytical characterization. Utilizing cutting-edge technologies and best practices, we deliver tailored solutions to meet each project's unique needs and regulatory requirements.

GMP Manufacturing

Our viral vector (GMP) manufacturing services follow an open-source concept, including state-of-the-art technologies, to ensure robust and scalable production processes, which meet the highest product quality requirements. We are able to provide processes for our various vector platforms (LV, AAV, AV & MVA) as well as process development and production for any customer derived platform in our brand-new biosafety level 2 QC labs and GMP facility up to 200L.

Quality Analytics

The diversity and complexity of virus and viral vector product development is demanding and challenging. Our analytical experts support and secure your candidate's individual analytical requirements with know-how and flexibility. The production and analytics of viruses and viral vectors is combined in our brand-new biosafety level 2 QC labs and GMP facility.

AAV Production

We are dedicated to advancing gene therapy and research through the development and production of high-quality AAV (adeno-associated virus) vectors. Our expertise, our cutting-edge technology, and our commitment to quality make us your ideal partner for your AAV vector production. We offer flexible, scalable solutions designed to meet the specific requirements of your project, from research and development to clinical trials and therapeutic applications.

Lentivirus Production

We offer integrated CDMO services to develop and manufacture lentiviral vectors. We can produce the viral vector by transient transfection, packaging, or producer cell line. As one stop-shop we cover all steps, from vector design and development to process development and GMP manufacturing to analytics, bioassays, QC and fill & finish. We rely on our Lenti.RiGHT^®packaging cell line as a production system to unlock the full potential of your lentiviral vector construct. Choose what works best for you from our flexible development and manufacturing services.

Poxvirus Production

Poxviruses carry and express large payloads. They are strong inducers of T-cell immunity and are especially suitable as boosters for vaccination and in virotherapies. We design and generate viral vectors for expression of multiple transgenes and optimize processes for specific viruses based on our proprietary production platform. Our rapid recombination system significantly shortens the timelines that are usually required for the generation of recombinant viruses. In a final step, we optimize a production process for your specific virus, based on the fully-characterized, continuous avian cell line AGE1.CR.pIX^®.