Our Expertise - Your Success
Meet our experienced management team with a deep understanding of industry dynamics and a keen sense of new trends.
Our Executive Team
Dr. Alfred Merz
Chief Operating Officer (COO), Interim Chief Executive Officer (CEO)
Alfred joined the company in 2024. Since then, he has assumed the role of COO and interim CEO. He brings over 30 years of international experience in manufacturing, operational excellence and strategy development with leading pharmaceutical and biotech companies, including Bayer and Novartis in Europe and the USA. Alfred holds a doctor of science in pharmacy from the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland.
Andrea Hauptmann
Chief Financial Officer (CFO)
Andrea has been with the company since 2009. She is responsible for financial reporting, controlling, funding, cash management, and financial risk management. Andrea was granted commercial procuration in 2009 and took on the responsibilities of CFO in 2021, having previously held the role of vice president finance and administration at ProBioGen. Before joining the company, she held a number of key financial management positions in the service and real estate sector. Andrea holds a degree in economics (German Diplom) from Technical University (TH) of Zittau, Germany.
Dr. Volker Sandig
Chief Scientific Officer (CSO)
Volker has been part of ProBioGen since 2000. In that year, he initiated the company's cell line development program, which resulted in the unique CHO.RiGHT® platform for protein production. He is the co-inventor of our key technologies, including the AGE1 designer cell lines, GlymaxX® and DirectedLuck®. His current work aims to modernize viral vector manufacturing and establish new platforms for RNA delivery. This includes customized design of suspension cell lines for viral vaccines as well as packaging and producer cell lines for gene therapy vectors. For his innovation and contribution to the field of animal cell culture technology, he received the inaugural 2019 ESACT Innovation Award. Prior to joining ProBioGen, he led a research group at Merck Research Laboratories, USA, focusing on the development of manufacturing systems for gutless adenoviruses and vectored vaccines. Volker holds a medical degree and received his doctorate in molecular biology from the Humboldt University of Berlin, Germany.
Dr. Gabriele Schneider
Chief Business Officer (CBO)
Gabriele joined ProBioGen in 2002 and has contributed significantly to the company’s growth and success. She became CBO in 2017 after holding several positions within the company and oversees business development, commercial, marketing and communications strategy. She has a proven track-record in deal making and in building strong and lasting relationships with clients and partners worldwide. After her academic career, she transitioned to the biotech industry in 2000 as a project manager at Kelman GmbH and was consulting small biotech companies before joining ProBioGen. Gabriele holds a doctorate from Humboldt University in Berlin, Germany and a master's degree in political science from Johann Wolfgang Goethe University in Frankfurt am Main, Germany.
Dr. René Brecht
Senior Vice President (SVP),Global Head of Manufacturing, Science & Technologies
René came to ProBioGen in 2002 and currently serves as SVP and global head of manufacturing, science, and technologies. He is responsible for process development up to GMP manufacturing of clinical materials. In addition, he oversees the alignment of manufacturing capabilities between our site and the late stage clinical and commercial manufacturing site in Egypt. Prior to joining ProBioGen, he held a position as research scientist at the University of Leipzig, where he was responsible for pre-clinical and GMP process development of monoclonal antibodies and antibody fragments for therapeutic and diagnostic purposes. René received his doctorate in pharmaceutical chemistry from the University of Marburg, Germany, in naturally occurring anticancer compounds.
Julian Collins
Senior Vice President (SVP),Head of People & Organizational Development
Julian has been SVP people and organizational development at ProBioGen and our subsidiary MiGenTra since 2023. He is responsible for strategic and operational human resource management, including organizational development, talent management, and all business activities along the employee lifecycle. Before joining us, he held a number of human resource management positions in the financial services, chemicals, and medical device sectors over the past 20 years. Julian holds a degree in psychology (German Diploma) from the Free University (FU) of Berlin, Germany as well as an MBA from the University of Wales, UK.
Susanne Kästner
Senior Vice President (SVP),Quality
Susanne has been with the company since 2022 as SVP Quality. She has held various positions with responsibility for global regulatory activities and various areas of quality assurance. Prior to joining ProBioGen, she was responsible for quality assurance at Novartis and FAREVA at the Austrian site for the production of sterile cytostatics. She is experienced in worldwide GMP- and regulatory requirements. She holds a Lean Six Sigma Green Belt and has experience as a lead investigator for data integrity events and as a lead auditor. Susanne studied chemistry at the Technical University (TU) in Berlin, Germany and holds a master's degree in drug regulatory affairs from the Rhenish Friedrich Wilhelm University of Bonn, Germany.
Dr. Lutz Hilbrich, Chief Executive Officer & Senator, Senate of Economy Europe
Dr. Lutz Hilbrich, Senator at Senate of Economy Europe, holds a Medical Degree from the Julius-Maximilians-University, Würzburg, Germany and an Executive MBA from Stern School of Business at NYU, USA. Before joining ProBioGen in June 2020 he was the Head of the Biosimilars Platform China for Sanofi and was previously second in command for the Biosimilars Business Unit at Boehriger Ingelheim GmbH, Germany. He is experienced in the end-to-end development and commercialization of Biologics, particularly Biosimilars, in Europe, North-America, Asia and Africa. Besides serving on a couple of organizational committees for international conferences on Biologics and Biosimilars, he sits on the Biosimilar Advisory Board of the American Conference Institute (ACI). In 2021 he incorporated ProBioGen’s first spin-off, MiGenTra GmbH. Lutz is member of the Scientific Advisory Board of Novel 351k, a US company.
Dr. Gabriele Schneider, Chief Business Officer
Chief Business Officer since November 2017 following 10 years as Vice President Business Development. Dr. Gabriele Schneider is responsible for commercial, business and communication strategy and manages all activities pertaining to business development. She has an established track record of building strong and lasting relationships with clients and partners worldwide. She joined the biotech industry in 2000 as Project Manager at Kelman GmbH and was consulting small biotech companies before joining ProBioGen in 2003. Gabriele holds a doctorate from Humboldt-Universität zu Berlin and a master’s degree in political science from Johann Wolfgang Goethe-Universität Frankfurt am Main, Germany.
Andrea Hauptmann, Chief Financial Officer
Vice President Finance & Administration at ProBioGen since 2015 and Chief Financial Officer since 2021. Andrea Hauptmann has been responsible for financial reporting, controlling, funding and cash management, risk management, human resources and administration since 2011. Before joining ProBioGen in 2009, she held a number of key financial management positions in the service and real estate sector. She was granted power of attorney in 2009. Andrea Hauptmann holds a diploma in from Technical University (TH) of Zittau, Germany.
Dr. Volker Sandig, Chief Scientific Officer
Dr. Volker Sandig initiated ProBioGen’s cell line development program in 2000 resulting in the unique CHO.RiGHT® platform for protein production. He is co-inventor of key ProBioGen technologies including AGE1 designer cell lines, GlymaxX® and DirectedLuck®. His current work aims at modernizing manufacture of viral vectors and establishing new platforms for RNA delivery. This includes customized design of suspension cell lines for viral vaccines as well as packaging and producer cell lines for gene therapy vectors. For his innovation and contribution to the field of Animal Cell Culture Technology he received the Inaugural 2019 ESACT Innovation Award. Prior to joining ProBioGen, he led a research group at Merck Research Laboratories, USA, focusing on the development of manufacturing systems for gutless adenoviruses and vectored vaccines. Volker Sandig holds a medical degree and received his doctorate in Molecular Biology from the Humboldt University, Berlin, Germany.
Dr. René Brecht, Senior Vice President, Global Head Manufacturing, Science & Technologies
Dr. René Brecht joined ProBioGen in 2002 and is our SVP and Global Head Manufacturing, Science & Technologies . René Brecht is responsible for process development up to GMP manufacturing of clinical materials. In addition, he oversees the alignement of manufacturing capabilities between our site and the late stage clinical and commercial manufacturing site in Egypt. Prior to joining ProBioGen, he held a position as Research Scientist at the University of Leipzig, where he was responsible for pre-clinical and GMP process development of monoclonal antibodies and antibody fragments for therapeutic and diagnostic purposes. René Brecht received his doctorate in Pharmaceutical Chemistry from the University of Marburg, Germany, on natural occurring anticancer compounds.
Dr. Marco Riedel, Senior Vice President, Head of Digital Transformation
Dr. Marco Riedel joined ProBioGen in 2000 and has held a number of management positions over the years. From 2016 to 2020, he was responsible for the company as project head for the rebuilding of a further site as far as obtaining the manufacturing authorization. Afterwards, Marco was assigned the responsibility for the company-wide digital transformation. Since 2004, Dr. Marco Riedel has served as a Qualified Person for drug substance certification and release. Dr. Marco Riedel studied chemistry at the Humboldt University in Berlin, Germany and obtained his doctorate at the University of Leipzig, Germany. He is active in several professional associations.
Susanne Kästner, Senior Vice President, Quality
Ms. Susanne Kästner studied Chemistry at the Technical University in Berlin, Germany and holds a Master Degree in Drug Regulatory Affairs from the Rhenish Friedrich Wilhelm University of Bonn. In various positions she was responsible for worldwide regulatory activities as well as different areas in Quality Assurance. Before joining ProBioGen, she was responsible for Quality Assurance for Novartis and FAREVA at the Austrian site for the production of sterile cytostatics. She is experienced in world-wide GMP- and regulatory requirements. She holds a Lean Six Sigma Greenbelt and has experience as a lead investigator for data integrity events and as a lead auditor.
Julian Collins, Senior Vice President, Head of People & Organizational Development
Senior Vice President People and Organizational Development at ProBioGen and MiGenTra since 2023. Julian is responsible for People Acquisition & Development, People Management and People Services. Before joining ProBioGen in 2023, Julian held a number of Human Resource Management positions in the financial service, chemical and medical devices sectors. Julian holds a diploma in psychology from Free University (FU) of Berlin, Germany as well as an MBA from University of Wales.
Our Supervisory Board
ProBioGen's supervisory board oversees the executive team and approves major corporate decisions. It comprises eight members, with Dr. Wafik Bardissi, chairman and CEO of the parent company Minapharm Pharmaceuticals, as chairman.
Dr. Wafik Bardissi, Chairman
Dr. Wafik Bardissi has been working in the pharmaceutical and biopharmaceutical industry for more than 30 years and has held various executive positions. He is the chairman and CEO of Minapharm Pharmaceuticals, a regional pharma and biopharma leader in Egypt and the Middle East. In 2001, Wafik founded the first state-of-the-art biotech manufacturing operation in Africa and the MENA region. In 2010, he signed the deal to acquire ProBioGen. He is also the founder and CEO of Amplifon Middle East s.a.e., a subsidiary of Amplifon spa, a multi-national world leader in hearing technology services. Following his studies in medicine and surgery, Wafik pursued his research interests in business information technology (MSc.), operational research (MSc.), and complex decision sciences and artificial intelligence (PhD) in the UK. In 2010, Wafik was honored with the Knighthood (cavalry) of the Pontifical Equestrian Order of St. Gregory the Great by his Holiness Pope Benedict XVI in recognition of his pioneering social work.
Dr. Shaheer Bardissi
Dr. Shaheer Bardissi serves as Co-CEO and executive board member at Minapharm Pharmaceuticals, an Egyptian biopharmaceutical company with multiple global subsidiaries. Shaheer is responsible for the growth strategy of the Minapharm group in the field of immuno-oncology, vaccines, and cell and gene-based therapies in collaboration, as well as Minapharm's biological portfolio expansion throughout the African continent. Shaheer previously worked at BioNTech and contributed to the successful development of immunotherapeutic technologies in the field of cell and gene therapy. Shaheer obtained his PhD from Johannes Gutenberg University, Mainz, Germany, with a focus on gene-based immunotherapy. Prior to that, he completed his master of science in molecular medicine at University College London, bachelor of science in biomedical sciences at King's College London, and also holds a master's of science in quantitative management science and healthcare data analytics from Duke University, North Carolina, USA.
Amr Shabrawishi, Co-Chairman
Amr Shabrawishi has been working in the medical, pharmaceutical, and biopharmaceutical fields for more than 25 years. He is the vice-chairman of Minapharm Pharmaceuticals, a leading regional pharma and biopharma manufacturer based in Egypt, with markets in Africa and the Middle East. He is also the chairman and CEO of Shabrawishi Hospital, a private multi-specialty hospital in Cairo, Egypt, the chairman of Egyptian Biological Science Co., a leading company for the collection and processing of blood and plasma for therapeutic usage, and a member of the board of directors of the British International School Cairo, the leading non-profit British school in Cairo. Amr Shabrawishi is member of the board of Viral Inactivated Plasma Systems (VIPS), a Swiss-based company with proprietary mini pool plasma viral inactivation and fractionation technology. He earned his bachelor's degree in medicine and surgery (MB, BCh.) from Cairo University.
Prof. Dr.-Ing. Wiltrud Treffenfeldt
Prof. Dr.-Ing. Wiltrud Treffenfeldt is an experienced leader who has held several executive leadership positions with multinational companies, including Dow, Dow AgroSciences, and Degussa/Evonik. She successfully built international teams in Europe, the United States, and Saudi Arabia. From 2011 – 2019, she was the chief technology officer for Europe, the Middle East, Africa, and India. During her tenure, she focused on customer innovation and co-creation. In her role, she actively supported the merger of Dow and DuPont and the consecutive split into 3 new companies. Since her retirement, she has been working as an independent consultant for SMEs and research organizations, where she uses her knowledge and experience in the chemical, agro, pharma, and industrial biotech industries. Throughout her entire career, Wiltrud was actively involved in scientific committees and organizations such as Dechema, OECD, GVC and VCI. She was a member of both bioeconomy councils of the German government and is a member of the senate of the Fraunhofer Gesellschaft. Since 2020, she has been a member of the supervisory board of the BRAIN Biotech AG. Her educational background is food & biotechnology (TU Berlin). She earned her professorship at the University Hannover, where she taught biochemical engineering for 17 years.
Richard Chambers
Klaus Nestler
Klaus Nestler has been a member of the supervisory board of ProBioGen since 2010. He is a managing director at ACXIT Capital, a Frankfurt-based investment bank, where he advises life sciences companies on M&A transactions as well as on financing and leveraged buyouts. Before joining ACXIT Capital, he was the founder and CEO of BioConnect AG, a specialist advisory firm focused on venture capital and M&A transactions for corporate customers in the biotechnology, medical technology, pharma, and diagnostics sectors. Klaus Nestler started his professional career with SBC Warburg, the investment banking arm of Swiss Bank Cooperation, where he advised on cross-border M&A transactions and capital market projects for companies in the healthcare sector, with assignments in London and Zurich. He holds a master's degree in economics from the University of Stuttgart-Hohenheim and was a banking apprentice at Dresdner Bank.
Prof. Dr. med. Hans-Dieter Volk
Prof. Dr. med. Hans-Dieter Volk, MDPHD, is a trained clinical immunologist and was the head of the Institute of Medical Immunology at the Charité - Universitätsmedizin Berlin until 2021. He was also the founding director and speaker of the BIH-Center for Regenerative Therapies (BCRT) and head of the department of immunology of the Labor Berlin-Charité Vivantes GmbH. He is now a senior professor at the Charité Universitätsmedizin Berlin. Prof. Volk's focus is on translational immunology, with an aim towards developing and implementing new diagnostic and therapeutic approaches. He has contributed to over 1,000 scientific papers (h-index >104). More specifically, his research includes the development of immune biomarkers for patient stratification and the monitoring of therapy response as well as new immunotherapeutic approaches in the fields of transplantation immunology, immunopathogenesis of virus infections in immunocompromised patients, and regenerative medicine. He is particularly interested in new cell and gene-based therapies. Transdisciplinary work and close collaboration with industry partners have allowed him to implement innovative new approaches. BCRT and the Institute of Medical immunology have generated a number of successful biotech spin-off companies, including Jerini AG, JPT GmbH, ProBioGen AG, Cellserve GmbH, Cytolon GmbH, and most recently CheckImmune GmbH. Prof. Volk has been actively involved (lead or steering committee) in several FP6/FP7/H2020/Horizon Europe EU-funded consortia, such as RISET, One study, BioDrim, PACE, HipGen, Reshape, RESTORE, and GeneTIGA.
Prof. Dr. Ralf Wagner
Ralf Wagner is Univ.-Prof. for medical microbiology (virology) at the Institute of Medical Microbiology and Hygiene, University of Regensburg, Germany. His team is involved in several aspects of vaccine research including preclinical and clinical development. He served as chair, co-chair, and board member of various public-funded vaccine clusters (e. g. EU, Gates Foundation, NIH, BMBF, Research Foundations). Ralf Wagner is an inventor and co-inventor of several patents and author of numerous peer-reviewed scientific publications. He is start-up ambassador for his University, consulting life-science venture funds and co-founder of several biotech companies. Amongst others, he established Geneart AG (Regensburg), a previously public biotech company. During his leadership (CEO/CSO; 2000-2012), Geneart grew to more than 230 employees and 2 subsidiaries in Canada and the US. He was awarded with Germany's Founders Award (Top 3), the "Step Award", and the "European Biotech Award". After the acquisition by Life Technologies Inc., he led the integration process and served as VP Synthetic Biology within the US Corporation (2010-2012).
Partners
The prodigious strides witnessed in scientific advancement over the past two decades have heralded an era of unprecedented technological innovation. At ProBioGen, we remain steadfastly attuned to this evolving landscape, meticulously scouring the global market and leveraging our extensive network to discern and appraise potential collaborators. Our approach to partnerships is characterized by collaboration imbued with purpose, as we work in concert with our counterparts to achieve targeted outcomes. With a steadfast commitment to delivering tangible value to our end customers, our collaborative endeavors are meticulously tailored to address specific objectives, ensuring optimal results and enduring satisfaction.
Thermo Fisher Scientific
We engineered the Freedom™ CHO-S™ Kit platform, which enables cost-and-time-efficient stable cell line development for research and commercial purposes, in close collaboration with Thermo Fisher Scientific. The kit is available via Thermo Fisher Scientific.
Boehringer Ingelheim
Boehringer Ingelheim has a non-exclusive license for ProBioGen’s proprietary GlymaxX® ADCC enhancement technology (Antibody-Dependent Cell-Mediated Cytotoxicity). Under this license, Boehringer Ingelheim applies GlymaxX® for third parties from its global contract manufacturing platform as well as to its own development candidates, to produce antibodies with enhanced ADCC potency.
References
Our customer range is extensive; some of our key customers and selected references are: